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Wei Ling Xian

The IC values of complete clematis saponin (CCS) on the cells of in-vitro cultured Ehrlich ascites carcinoma (EAC), S180 ascites carcinoma (S180A), and hepatic ascites carcinoma (HepA ...

Wei Ling Xian
Clematidis Radix, Clematis

Dosage
The decoction is orally taken at a dose of 6-9g, or up to 30g for being choked by fish bone.
Toxicity
Prolonged exposure to protoanemonin can cause skin effervesce and mucosal hyperemia. It is easy for protoanemonin to polymerize into anemonin, which is a toxic component of Wei Ling Xian, and overdose of which can lead to poisoning.
Chemical Composition
Protoanemonin; Saponin; Hederagenin; Epihederagenin; Oleanolic acid; Aglycone; CP0-10, 2a, 3a, 7a, 8a, 9a, 10a, 2b and 3b.(1)
Precautions
1.Exercise caution when administering this herb to pregnant women and to patients with qi and blood deficiencies.
2.Adhere to recommended safe dosage to prevent herb poisoning.
Pharmacology
The IC50 values of complete clematis saponin (CCS) on the cells of in-vitro cultured Ehrlich ascites carcinoma (EAC), S180 ascites carcinoma (S180A), and hepatic ascites carcinoma (HepA) are 242mg/ml, 193mg/ml and 130mg/ml, respectively. The tumor-weight-inhibiting rates of CCS at 0.25g/kg, 0.5g/kg and 1g/kg on transplanted sarcoma S180 in mice are 40.3%, 55.1% and 53.0%, respectively. These statistics suggest that Wei Ling Xian has anti-tumor effects. CCS (at 0.2g/kg, 0.4g/kg and 0.8g/kg) does not, however, seem to significantly affect mice's survival time from S180A.(2)
References
  1. Editorial Committee of Chinese Materia Medica. State Drug Administration of China. Chinese Materia Medica. Shanghai: Science and Technology Press; 1998.
  2. Qiu Guang Qing, et al. Journal of Traditional Chinese Medicinal Material. 1999;22(7):351-353.
This information is educational in context and is not to be used to diagnose, treat or cure any disease. Please consult your licensed health care practitioner before using this or any medical information.
©2000-2008 ADCCG, Inc. All Rights Reserved.

    
 
  Welcome to the DirectoryM Guide for Comedy Clubs
The IC values of complete clematis saponin (CCS) on the cells of in-vitro cultured Ehrlich ascites carcinoma (EAC), S180 ascites carcinoma (S180A), and hepatic ascites carcinoma (HepA ...
Jia Kang Ling Pian mainly functions to calm the liver, to suppress hyperactivity of the liver yang and to soften and resolve hard mass.
Wu Ling San primarily functions to warm yang and reinforce vital energy, remove dampness by diuresis and promote the flow of qi.
Gui Zhi Fu Ling Wan promotes blood circulation, removes blood stasis, and eventually eliminates mass in the abdomen.
In healthy people, the normal regulatory functions of the nervous system, the endocrine system, and the kidney help maintain a functional water metabolic balance, which prevents the occurrence of edema even in the case of excessive water intake.
Zhu Ling can reduce the occurrence rate of B-butyl-N-(4-hydroxybutyl) nitrosamine (BBN)-induced bladder tumors in rats, the number of tumors per rat, the tumor diameter, and the tumor malignity.
 
 
 
 
 
 
 
 
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